Microsphere core technology boosts innovation of biopharmaceutical industry chain

Authors

Jie WU, State Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China; School of Chemical Engineering, University of Chinese Academy of Sciences, Beijing 100049, ChinaFollow
Weiqing ZHOU, State Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China; School of Chemical Engineering, University of Chinese Academy of Sciences, Beijing 100049, China
Lan ZHAO, State Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China; School of Chemical Engineering, University of Chinese Academy of Sciences, Beijing 100049, China
Guanghui MA, State Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China; School of Chemical Engineering, University of Chinese Academy of Sciences, Beijing 100049, ChinaFollow

Keywords

biopharmaceutical; microspheres; cell culture; bioseparation; delivery vector

Document Type

Biomanufacturing: Retrospect and Prospects

Abstract

Advancements in life science and biotechnology have boosted the evolution of the biopharmaceutical industry with the continual emergence of biomedical products for disease prevention, diagnosis, and treatment. Microspheres, as crucial functional materials, play a significant role in the discovery, preparation, separation, and delivery of biological drugs due to their flexible size, morphology, structure, and function. This study reviews recent significant advancements in microspheres and their applications in cell culture, chromatographic separation, drug delivery, and as vaccine adjuvants. Additionally, it proposes future trends for the development of microspheres.

First page

79

Last Page

90

Language

Chinese

Publisher

Bulletin of Chinese Academy of Sciences

References

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Recommended Citation

WU, Jie; ZHOU, Weiqing; ZHAO, Lan; and MA, Guanghui (2024) "Microsphere core technology boosts innovation of biopharmaceutical industry chain," Bulletin of Chinese Academy of Sciences (Chinese Version): Vol. 40 : Iss. 1 , Article 8.
DOI: https://doi.org/10.16418/j.issn.1000-3045.20241130002
Available at: https://bulletinofcas.researchcommons.org/journal/vol40/iss1/8