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Bulletin of Chinese Academy of Sciences (Chinese Version)

Keywords

terpenoids; synthetic biology; chemical semi-synthesis; scale-up; artificial intelligence

Document Type

Biomanufacturing: Retrospect and Prospects

Abstract

Terpenoids, a class of chemical entities with diverse biological activities in nature, demonstrate significant potential for applications in fields such as drug discovery, flavor industry, and agriculture. However, traditional methods face challenges, including inefficiency and high costs, in the discovery and industrialization of terpenoids. The rapid development of synthetic biology, genomics, artificial intelligence, and automation provides new opportunities for efficient terpenoid discovery and industrialization. This study comprehensively analyzes how these technologies synergistically contribute to the discovery, optimization, and large-scale production of terpenoids, and summarizes the current high-yield situations of terpenoids. The aim is to propose innovative strategies to accelerate technological innovation and industrial upgrading in this field.

First page

47

Last Page

66

Language

Chinese

Publisher

Bulletin of Chinese Academy of Sciences

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