Bulletin of Chinese Academy of Sciences (Chinese Version)


molecular modules; designer breeding; innovation system

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With over 1.3 billion people, food security is always the No. 1 issue in the governmental agenda in China, and sustainable food production requires innovation in crop breeding. This paper outlines the research effort and output of the past five years of a grand project of Chinese Academy of Sciences of the Innovation System of Designer Breeding by Molecular Modules, and provides a few examples of how to combine the cutting-edge theories and technologies of life sciences to design rice varieties and other species. The achievements demonstrate that the project has made substantial progresses in designer breeding by using molecular modules.

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Bulletin of Chinese Academy of Sciences


韩一军, 郝晓燕. 2017年中国农产品贸易发展特点及未来展望.农业展望, 2018, (3):88-92.

吴金华, 张迟, 耿业朋, 等.全球种业现状及发展趋势分析.安徽化工, 2017, 43(1):12-14.

Meuwissen T H, Hayes B J, Goddard M E. Prediction of total genetic value using genome-wide dense marker maps. Genetics, 2001, 157(4):1819-1829.

Watson A, Ghosh S, Williams M J, et al. Speed breeding is a powerful tool to accelerate crop research and breeding. Nature Plants, 2018, 4:23-29.

薛勇彪, 段子渊, 种康, 等.面向未来的新一代生物育种技术——分子模块设计育种.中国科学院院刊, 2013, 28(3):308-314.

薛勇彪, 种康, 韩斌, 等.开启中国设计育种新篇章——"分子模块设计育种创新体系"战略性先导科技专项进展.中国科学院院刊, 2015, 30(3):393-402.

Ma Y, Dai X, Xu Y, et al. COLD1 confers chilling tolerance in rice. Cell, 2015, 160(6):1209-1221.

Huang X, Yang S, Gong J, et al. Genomic architecture of heterosis for yield traits in rice. Nature, 2016, 537(7622):629-633.

Deng Y, Zhai K, Xie Z, et al. Epigenetic regulation of antagonistic receptors confers rice blast resistance with yield balance. Science, 2017, 355(6328):962-965.