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Bulletin of Chinese Academy of Sciences (Chinese Version)

Keywords

synthetic biology; biofoundry; engineering platform

Document Type

Article

Abstract

In the field of synthetic biology research, the massive scale of trial-and-error experiments in engineering goes far beyond the traditional labor-intensive research paradigm, so it needs a transformative engineering research platform. With the introduction of various types of intelligent equipment to meet the production needs, engineering platforms carry out a large-scale of customization and research paradigm innovation, to realize the remote customization, offsite design, and economic scale production of organisms. Engineering platforms can accumulate experience and knowledge quickly, and serve as the scientific basis for the predictive synthesis of organisms. This article will introduce some cases and development trends of engineering platforms, as well as upstream and downstream institutions for synthetic biology research.

First page

1249

Last Page

1257

Language

Chinese

Publisher

Bulletin of Chinese Academy of Sciences

References

Clarke L J, Kitney R I. Synthetic biology in the UK-An outline of plans and progress. Synthetic and Systems Biotechnology, 2016, 1(4):243-257.

晁然, 原永波, 赵惠民.构建合成生物学制造厂.中国科学:生命科学, 2015, 45(10):976-984.

Le Feuvre R A, Scrutton N S. A living foundry for Synthetic Biological Materials:A synthetic biology roadmap to new advanced materials. Synthetic and Systems Biotechnology, 2018, 3(2):105-112.

DARPA's Living Foundries Project Report.[2018-10-26]. https://www.darpa.mil/program/living-foundries.

Eric Lax. The Mold in Dr. Florey's Coat:The Story of the Penicillin Miracle. New York:Henry Holt and Company, 2004.

Morrell W C, Birkel G W, Forrer M, et al. The experiment data depot:a web-based software tool for biological experimental data storage, sharing, and visualization. ACS Synthetic Biology, 2017, 6(12):2248-2259.

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