synthetic cell; synthetic bacteria; synthetic virus; synthetic phage
In the field of medical applications, synthetic biology researchers design genetic circuits to modify human cells, or to modify synthetic organisms such as bacteria and viruses and make them interact with the human body. These artificially designed organisms are capable of perceiving disease-specific signals or artificial signals, targeting abnormal cells and foci, expressing reporter molecules or releasing therapeutic drugs, thus enabling the monitoring of human physiological conditions and the diagnosis and treatment of typical diseases such as tumors, metabolic diseases, and drug-resistant bacteria infections. This article will comprehensively describe some recent research progress.
Bulletin of Chinese Academy of Sciences
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Jinming, CUI; Liwei, WANG; Zhiguang, CHANG; Zhongsheng, ZANG; and Chenli, LIU
"Progress of Synthetic Biology Research in Medical Applications,"
Bulletin of Chinese Academy of Sciences (Chinese Version): Vol. 33
, Article 10.
Available at: https://bulletinofcas.researchcommons.org/journal/vol33/iss11/10