non-coding RNA; microRNA; RNA interference; insect resistance
Non-coding RNAs (ncRNAs), including long non-coding RNAs (lncRNAs) and small RNAs such as microRNAs (miRNAs) and short interference RNAs (siRNAs), exist widely in eukaryotes and affect gene expressions at different levels. In plant, ncRNAs are involved in growth, development, response to biotic and abiotic stresses, and are important players in epigenetics. RNA interference (RNAi) refers to homology gene silencing caused by double strand RNAs (dsRNAs) and is a major mechanism of gene expression regulation by ncRNAs. Since discovery, RNAi has been developed as a powerful technology for genetic analysis, gene therapy, and plant protection. In this review, we summarize the recent progresses in research of the function and mechanism of ncRNAs in plant defense pathways and discuss the application of RNAi technology in agricultural pest control.
Bulletin of Chinese Academy of Sciences
Lee R C, Feinbaum R L, Ambros V. The C. elegans heterochronic gene lin- 4 encodes small rnas with antisense complementarity to lin- 14. Cell, 1993, 75(5):843-854.
Napoli C, Lemieux C, Jorgensen R. Introduction of a chimeric chalcone synthase gene into petunia results in reversible cosuppression of homologous genes in trans. Plant Cell, 1990, 2(4):279-289.
Waterhouse P M, Graham H W, Wang M B. Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA. Proc Natl Acad Sci USA, 1998, 95(23):13959-13964.
Fire A, Xu S Q, Montgomery M K, et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature, 1998, 391(6669):806-811.
Hou W N, Duan C G, Fang R X, et al. Satellite RNA reduces expression of the 2b suppressor protein resulting in the attenuation of symptoms caused by Cucumber mosaic virus infection. Mol Plant Pathol, 2011, 12(6):595-605.
Katiyar-Agarwal S, Jin H. Role of small RNAs in host-microbe interactions. Annu Rev Phytopathol, 2010, 48:225-246.
Szittya G, Burgyan J. RNA interference-mediated intrinsic antiviral immunity in plants. Curr Top Microbiol Immunol, 2013, 371:153-181.
Zhu C, Ding Y, Liu H. MiR398 and plant stress responses. Physiol Plant, 2011, 143(1):1-9.
Navarro L, Dunoyer P, Jay F, et al. A plant miRNA contributes to antibacterial resistance by repressing auxin signaling. Science, 2006, 312(5772):436-439.
Zhang X, Zhao H, Gao S, et al. Arabidopsis Argonaute 2 regulates innate immunity via miRNA393( *)-mediated silencing of a Golgilocalized SNARE gene, MEMB12. Mol Cell, 2011, 42(3):356-366.
Verma V, Ravindran P, Kumar P P. Plant hormone-mediated regulation of stress responses. BMC Plant Biol, 2016, 16:86.
Harfouche A L, Shivaji R, Stocker R, et al. Ethylene signaling mediates a maize defense response to insect herbivory. Mol Plant Microbe Interact, 2006, 19(2):189-199.
Onkokesung N, Baldwin I T, Galis I. The role of jasmonic acid and ethylene crosstalk in direct defense of Nicotiana attenuata plants against chewing herbivores. Plant Signal Behav, 2010, 5(10):1305-1307.
Pandey S P, Baldwin I T. RNA-directed RNA polymerase 1 (RdR1) mediates the resistance of Nicotiana attenuata to herbivore attack in nature. Plant J, 2007, 50(1):40-53.
Pandey S P, Shahi P, Gase K, et al. Herbivory-induced changes in the small-RNA transcriptome and phytohormone signaling in Nicotiana attenuata. Proc Natl Acad Sci USA, 2008, 105(12):4559-4564.
Zhang X, Zhu Y, Liu X, et al. Plant biology. Suppression of endogenous gene silencing by bidirectional cytoplasmic RNA decay in Arabidopsis. Science, 2015, 348(6230):120-123.
Potuschak T, Vansiri A, Binder B M, et al. The exoribonuclease XRN4 is a component of the ethylene response pathway in Arabidopsis. Plant Cell, 2006, 18(11):3047-3057.
Yu N, Cai W J, Wang S, et al. Temporal control of trichome distribution by microRNA156-targeted SPL genes in Arabidopsis thaliana. Plant Cell, 2010, 22(7):2322-2335.
Ma Z X, Hu X P, Cai W J, et al. Arabidopsis mir171-targeted scarecrow-like proteins bind to GT cis-elements and mediate gibberellin-regulated chlorophyll biosynthesis under light conditions. PLoS Genetics, 2014, 10(8):e1004519.
Xue X Y, Zhao B, Chao L M, et al. Interaction between two timing microRNAs controls trichome distribution in Arabidopsis. PLoS Genet, 2014, 10(4):e1004266.
Gou J Y, Felippes F F, Liu C J, et al. Negative regulation of anthocyanin biosynthesis in Arabidopsis by a miR156-targeted SPL transcription factor. Plant Cell, 2011, 23(4):1512-1522.
Pichersky E, Gang D R. Genetics and biochemistry of secondary metabolites in plants:an evolutionary perspective. Trends Plant Sci, 2000, 5(10):439-445.
Falara V, Amarasinghe R, Poldy J, et al. The production of a key floral volatile is dependent on UV light in a sexually deceptive orchid. Ann Bot, 2013, 111(1):21-30.
Kessler A, Baldwin I T. Defensive function of herbivore-induced plant volatile emissions in nature. Science, 2001, 291(5511):2141-2144.
Maffei H V, Vicentini A P. Prospective evaluation of dietary treatment in childhood constipation:high dietary fiber and wheat bran intake are associated with constipation amelioration. J Pediatr Gastroenterol Nutr, 2011, 52(1):55-59.
Yu Z X, Wang L J, Zhao B, et al. Progressive regulation of sesquiterpene biosynthesis in Arabidopsis and patchouli ( Pogostemon cablin) by the miR156-targeted SPL transcription factors. Mol Plant, 2014, 8(1):98-110.
Schommer C, Palatnik J F, Aggarwal P, et al. Control of jasmonate biosynthesis and senescence by miR319 targets. PLoS Biol, 2008, 6(9):e230.
Rubio-Somoza I, Zhou C M, Confraria A, et al. Temporal control of leaf complexity by miRNA-regulated licensing of protein complexes. Curr Biol, 2014, 24(22):2714-2719.
Agrawal A A, Laforsch C, Tollrian R. Transgenerational induction of defences in animals and plants. Nature, 1999, 401(6748):60-63.
Holeski L M. Within and between generation phenotypic plasticity in trichome density of Mimulus guttatus. J Evolution Biol, 2007, 20(6):2092-2100.
Chinnusamy V, Zhu J K. Epigenetic regulation of stress responses in plants. Curr Opin Plant Biol, 2009, 12(2):133-139.
Zhong S H, Liu J Z, Jin H, et al. Warm temperatures induce transgenerational epigenetic release of RNA silencing by inhibiting siRNA biogenesis in Arabidopsis. Proc Natl Acad Sci USA, 2013, 110(22):9171-9176.
Hamilton A J, Baulcombe D C. A species of small antisense RNA in posttranscriptional gene silencing in plants. Science, 1999, 286(5441):950-952.
Rasmann S, De Vos M, Casteel C L, et al. Herbivory in the previous generation primes plants for enhanced insect resistance. Plant Physiol, 2012, 158(2):854-863.
Mao Y B, Cai W J, Wang J W, et al. Silencing a cotton bollworm P450 monooxygenase gene by plant-mediated RNAi impairs larval tolerance of gossypol. Nat Biotechnol, 2007, 25(11):1307-1313.
Baum J A, Bogaert T, Clinton W, et al. Control of coleopteran insect pests through RNA interference. Nature Biotechnology, 2007, 25(11):1322-1326.
Pitino M, Coleman A D, Maffei M E, et al. Silencing of aphid genes by dsRNA feeding from plants. PLoS One, 2011, 6(10):e25709.
Upadhyay S K, Chandrashekar K, Thakur N, et al. RNA interference for the control of whiteflies ( Bemisia tabaci) by oral route. J Biosci, 2011, 36(1):153-161.
Panwar V, Mccallum B, Bakkeren G. Host-induced gene silencing of wheat leaf rust fungus Puccinia triticina pathogenicity genes mediated by the Barley stripe mosaic virus. Plant Mol Biol, 2013, 81(6):595-608.
Alakonya A, Kumar R, Koenig D, et al. Interspecific RNA interference of SHOOT MERISTEMLESS-like disrupts Cuscuta pentagona plant parasitism. Plant Cell, 2012, 24(7):3153-3166.
Mao Y B, Tao X Y, Xue X Y, et al. Cotton plants expressing CYP6AE14 double-stranded RNA show enhanced resistance to bollworms. Transgenic Res, 2011, 20(3):665-673.
Wu X M, Yang C Q, Mao Y B, et al. Targeting insect mitochondrial complex I for plant protection. Plant Biotechnol J, 2016, 14(9):1925-1935.
Mao Y B, Xue X Y, Tao X Y, et al. Cysteine protease enhances plant-mediated bollworm RNA interference. Plant Mol Biol, 2013, 83(1-2):119-129.
Zhang J, Khan S A, Hasse C, et al. Pest control. Full crop protection from an insect pest by expression of long doublestranded RNAs in plastids. Science, 2015, 347(6225):991-994.
Jin S, Singh N D, Li L, Zhang X, et al. Engineered chloroplast dsRNA silences cytochrome p450 monooxygenase, V-ATPase and chitin synthase genes in the insect gut and disrupts Helicoverpa armigera larval development and pupation. Plant Biotechnol J, 2015, 13(3):435-446.
Lauressergues D, Couzigou J M, Clemente H S, et al. Primary transcripts of microRNAs encode regulatory peptides. Nature, 2015, 520(7545):90-93.
Wang M, Weiberg A, Lin F M, et al. Bidirectional cross-kingdom RNAi and fungal uptake of external RNAs confer plant protection. Nat Plants, 2016, 2:16151.
Zhang T, Zhao Y L, Zhao J H, et al. Cotton plants export microRNAs to inhibit virulence gene expression in a fungal pathogen. Nature Plants, 2016, 2(10):16153.
Ying-Bo, Mao; Dian-Yang, Chen; and Xiao-Ya, Chen
"Advances in Research of Plant Non-coding RNAs and RNAi-based Technology Against Insects Herbivore,"
Bulletin of Chinese Academy of Sciences (Chinese Version): Vol. 32
, Article 2.
Available at: https://bulletinofcas.researchcommons.org/journal/vol32/iss8/2