Big life-science: Study of omics from microscopic to mesoscopic scales

Authors

Jiarui WU, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China Institute for Proactive Healthcare, Shanghai Jiao Tong University, Shanghai 200030, ChinaFollow

Keywords

big life-science, omics, cell atlas, spatial omics, big data

Document Type

High Ground of Science and Innovation

Abstract

The human genome project at the turn of the century opened a new era of life science research and formed various omics characterized by holistic high-throughput research. The initial omics research was mainly carried out at the molecular level, such as genomics, transcriptomics, proteomics, etc., showing a new paradigm of data-driven research. With the development of research technologies, the omics research has risen to the mesoscopic level, the representative is the “Human Cell Atlas” project launched in 2017. At present, researchers have been able to carry out omics research at the level of tissues, organs, and even individuals, and resulted in the understanding complex life systems by integrating different levels of omics data.

First page

832

Last Page

839

Language

Chinese

Publisher

Bulletin of Chinese Academy of Sciences

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Recommended Citation

WU, Jiarui (2024) "Big life-science: Study of omics from microscopic to mesoscopic scales," Bulletin of Chinese Academy of Sciences (Chinese Version): Vol. 39 : Iss. 5 , Article 5.
DOI: https://doi.org/10.16418/j.issn.1000-3045.20240128001
Available at: https://bulletinofcas.researchcommons.org/journal/vol39/iss5/5