crop; pathogens and insect pests; bio-interactions; pest control
Pathogens and insect pests are the most formidable threats to sustainable crop production in China as well as the rest of the world. At present, the most common method of pest control is the use of chemical pesticides that target the basic metabolism, physiological and biochemical processes, and nerve receptors of pests and microbial organisms, leading to poisoning of humans and animals, agricultural pollution, and ecological damage. A great breakthrough in the next generation of pest control will be the artificial manipulation of bioinformation exchanges among crop, insect pests, and pathogenic microbial organisms. Decoding the molecular mechanisms of biointeractions is also one of the hot and frontier research areas in life sciences. The scientific discoveries and technological progress in this area, for example, the finding of RNAi phenomenon, discovery of immune receptor of eukaryotes, establishment of plant transformation technology and TALEN genome editing technology, have made paradigm shifts to the progress of entire life sciences. The strategic priority research project called Decoding the Mechanisms of Bio-interactions for Targeted Management of Agricultural Pests is the first and largest multi-disciplinary research program that sponsored by Chinese Academy of Sciences (CAS). The project aims to decode the complex biological interaction mechanisms and to translate basic research knowledge to cutting-edge approaches for smarter pest and disease managements. Within just a short period of three years, this project has made great progress. A series of high impact papers were published and it produced creative approaches for pest control. These significant achievements elevate the level of China's insect and pathology sciences to a world-class and contribute to the crop protection from pest infections without compromising agricultural productivity and environmental health.
Bulletin of Chinese Academy of Sciences
Brown L R. Who will feed China? Wake up call for a small planet. Worldwatch Institute:W W Norton & Co, 1994.
Foley J A, Ramankutty N, Brauman K A, et al. Solutions for a cultivated planet. Nature, 2011, 478:337-342.
Bragard C, Caciagli P, Lemaire O, et al. Status and prospects of plant virus control through interference with vector transmission. Annual Review of Phytopathology, 2013, 51:177-201.
Gilbertson R L, Batuman O, Webster C G, et al. Role of the insect supervectors Bemisia tabaci and Frankliniella occidentalis in the emergence and global spread of plant viruses. Annual Review of Virology, 2015, 2:67-93.
Li R, Weldegergis B T, Li J, et al. Virulence factors of geminivirus interact with MYC2 to subvert plant resistance and promote vector performance. The Plant Cell, 2014, 26:4991-5008.
Wu D, Qi T, Li W X, et al. Viral effector protein manipulates host hormone signaling to attract insect vectors. Cell Research, 2017, 27:402-415.
Pehrsson E C, Tsukayama P, Patel S, et al. Interconnected microbiomes and resistomes in low-income human habitats. Nature, 2016, 533:212-216.
Song W Y, Wang G L, Chen L L, et al. A receptor kinase-like protein encoded by the rice disease resistance gene, Xa21. Science, 1995, 270:1804-1806.
Baulcombe D C. RNA as a target and an initiator of posttranscriptional gene silencing in transgenic plants. Plant Molecular Biology, 1996, 32:79-88.
Van Montagu M, Schell J. The Ti plasmids of Agrobacterium. Current Topics in Microbiology and Immunology, 1982, 96:237-254.
Gu K, Yang B, Tian D, et al. R gene expression induced by a typeⅢ effector triggers disease resistance in rice. Nature, 2005, 435:1122-1125.
Yang M, Wang Y, Jiang F, et al. miR-71 and miR-263 jointly regulate target genes chitin synthase and chitinase to control locust molting. PLoS Genetics, 2016, 12:e1006257.
He J, Chen Q, Wei Y, et al. MicroRNA-276 promotes egg-hatching synchrony by up-regulating brm in locusts. Proceedings of the National Academy of Sciences of the United States of America, 2016, 113:584-589.
Zhou Z, Wu Y, Yang Y, et al. An Arabidopsis plasma membrane proton ATPase modulates JA signaling and is exploited by the Pseudomonas syringae effector protein AvrB for stomatal invasion. The Plant Cell, 2015, 27:2032-2041.
Du M, Zhai Q, Deng L, et al. Closely related NAC transcription factors of tomato differentially regulate stomatal closure and reopening during pathogen attack. The Plant Cell, 2014, 26:3167-3184.
Wang G, Roux B, Feng F, et al. The decoy substrate of a pathogen effector and a pseudokinase specify pathogen-induced modifiedself recognition and immunity in plants. Cell Host & Microbe, 2015, 18:285-295.
Wu G, Liu S, Zhao Y, et al. ENHANCED DISEASE RESISTANCE4 associates with CLATHRIN HEAVY CHAIN2 and modulates plant immunity by regulating relocation of EDR1 in Arabidopsis. The Plant Cell, 2015, 27:857-873.
Wang L, Pan Y, Yuan Z H, et al. Two-component signaling system VgrRS directly senses extracytoplasmic and intracellular iron to control bacterial adaptation under iron depleted stress. PLoS Pathogens, 2016, 12:e1006133.
Mao Y B, Liu Y Q, Chen D Y, et al. Jasmonate response decay and defense metabolite accumulation contributes to age-regulated dynamics of plant insect resistance. Nature Communications, 2017, 8:13925.
Hu X, Xiao G, Zheng P, et al. Trajectory and genomic determinants of fungal-pathogen speciation and host adaptation. Proceedings of the National Academy of Sciences of the United States of America, 2014, 111:16796-16801.
Feng P, Shang Y, Cen K, et al. Fungal biosynthesis of the bibenzoquinone oosporein to evade insect immunity. Proceedings of the National Academy of Sciences of the United States of America, 2015, 112:11365-11370.
Zhao L, Zhang X, Wei Y, et al. Ascarosides coordinate the dispersal of a plant-parasitic nematode with the metamorphosis of its vector beetle. Nature Communications, 2016, 7:12341.
Sun Y, Guo H, Yuan L, et al. Plant stomatal closure improves aphid feeding under elevated CO 2. Global Change Biology, 2015, 21:2739-2748.
Wang Y, Cheng X, Shan Q, et al. Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew. Nature Biotechnology, 2014, 32:947-951.
Zhang T, Zhao Y L, Zhao J H, et al. Cotton plants export microRNAs to inhibit virulence gene expression in a fungal pathogen. Nature Plants, 2016, 2:16153.
Zhang T, Jin Y, Zhao J H, et al. Host-induced gene silencing of the target gene in fungal cells confers effective resistance to the cotton wilt disease pathogen Verticillium dahliae. Molecular Plant, 2016, 9:939-942.
Lu M, J. H, Sun J. The role of symbiotic microbes in insect invasions. Annual Review of Ecology, Evolution, and Systematics, 2016, 47:487-505.
Wei, Qian; Jing, Qu; and Le, Kang
"Decoding Mechanisms of Bio-interactions for Targeted Management of Agricultural Pests,"
Bulletin of Chinese Academy of Sciences (Chinese Version): Vol. 32
, Article 1.
Available at: https://bulletinofcas.researchcommons.org/journal/vol32/iss8/1